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postherpetic neuralgia : ウィキペディア英語版
postherpetic neuralgia

Postherpetic neuralgia is a nerve pain due to damage caused by the varicella zoster virus. Typically, the neuralgia is confined to a dermatomic area of the skin, and follows an outbreak of herpes zoster (commonly known as shingles) in that same dermatomic area. The neuralgia typically begins when the herpes zoster vesicles have crusted over and begun to heal, but can begin in the absence of herpes zoster—a condition called ''zoster sine herpete'' (see Herpes zoster).
Treatment options for postherpetic neuralgia include antidepressants, anticonvulsants (such as gabapentin, pregabalin, or topiramate), gabapentin enacarbil (a prodrug of gabapentin) and topical agents such as lidocaine patches or capsaicin lotion. Opioid analgesics may also be appropriate in many situations. There are some sporadically successful experimental treatments, such as rhizotomy (severing or damaging the affected nerve to relieve pain) and TENS (a type of electrical pulse therapy).
==Signs and symptoms==
Symptoms:
* With resolution of the herpes zoster eruption, pain that continues for three months or more is defined as postherpetic neuralgia.
* Pain is variable, from discomfort to very severe, and may be described as burning, stabbing, or gnawing.
Signs:
* Area of previous herpes zoster may show evidence of cutaneous scarring.
* Sensation may be altered over the areas involved, in the form of either hypersensitivity or decreased sensation.
* In rare cases, the patient might also experience muscle weakness, tremor, or paralysis if the nerves involved also control muscle movement.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「postherpetic neuralgia」の詳細全文を読む



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